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Dosimetry (Stratos)

Stratos

Research Dosimetry Solution


The STRATOS Dosimetry Solution is an advanced research software package for 3D voxelized dose calculation in nuclear medicine, using SPECT/CT and PET/CT data. It allows the calculation and visualization of patient-specific dose maps for targeted radionuclide therapies.

Key features of the STRATOS Dosimetry Solution:

• complete workflow for multiple 3D images, including registration, segmentation and visualization
• calculation of voxel-wise residence-time maps
• calculation of voxel-wise energy-dose distributions using different approaches:

    • convolution using Dose-Volume-Kernel (DVK), according to MIRD pamphlet 17

    • Local Deposition Method (LDM)

• supported therapy isotopes: I131, Y90, Lu177, Ho166, Rh188, P32, Sm153 (others on request)
• support for all SPECT and PET imaging isotopes, enabling both prospective as well as retrospective studies
• calculation of dose statistics and Dose-Volume-Histograms per region
• tissue density correction based on the CT scan
• HTML report with key results and images from the analysis

 

You can also use planar images as input for the calculation of 3D maps in dosimetry imaging procedures.


This means that you can adapt the analysis to your clinical workflow and use a combination of 3D scans and planar images, considerably shortening the overall imaging time.

Note: STRATOS is an additional module for imalytics sold separately

  • 3D VOI definition on SPECT/CT images for a Lu177-DOTATOC therapy case

  • 3D dose map fused with CT data; dose statistics and dose-volume-histogram for a Lu177-DOTATOC therapy case

  • 3D dose map fused with CT data; dose statistics and dose-volume-histogram for a Y90 SIRT case

  • Registration of a planar scintigraphy image to a 3D CT in Stratos+

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Images

  • 3D VOI definition on SPECT/CT images for a Lu177-DOTATOC therapy case

    3D VOI definition on SPECT/CT images for a Lu177-DOTATOC therapy case

  • 3D dose map fused with CT data; dose statistics and dose-volume-histogram for a Lu177-DOTATOC therapy case

    3D dose map fused with CT data; dose statistics and dose-volume-histogram for a Lu177-DOTATOC therapy case

  • 3D dose map fused with CT data; dose statistics and dose-volume-histogram for a Y90 SIRT case

    3D dose map fused with CT data; dose statistics and dose-volume-histogram for a Y90 SIRT case

  • Registration of a planar scintigraphy image to a 3D CT in Stratos+

    Registration of a planar scintigraphy image to a 3D CT in Stratos+

  • 3D VOI definition on SPECT/CT images for a Lu177-DOTATOC therapy case

    3D VOI definition on SPECT/CT images for a Lu177-DOTATOC therapy case

  • 3D dose map fused with CT data; dose statistics and dose-volume-histogram for a Lu177-DOTATOC therapy case

    3D dose map fused with CT data; dose statistics and dose-volume-histogram for a Lu177-DOTATOC therapy case

  • 3D dose map fused with CT data; dose statistics and dose-volume-histogram for a Y90 SIRT case

    3D dose map fused with CT data; dose statistics and dose-volume-histogram for a Y90 SIRT case

  • Registration of a planar scintigraphy image to a 3D CT in Stratos+

    Registration of a planar scintigraphy image to a 3D CT in Stratos+

3D VOI definition on SPECT/CT images for a Lu177-DOTATOC therapy case
3D dose map fused with CT data; dose statistics and dose-volume-histogram for a Lu177-DOTATOC therapy case
3D dose map fused with CT data; dose statistics and dose-volume-histogram for a Y90 SIRT case
Registration of a planar scintigraphy image to a 3D CT in Stratos+

Special Case:

Click here to learn more about the possibility of personalized dosimetry with Yttrium 90


Publications

 
Goedicke A, Berker Y, Verburg FA, Behrendt FF, Winz O, Mottaghy FM. 
Medical Imaging, Volume 32, Issue 3, March 2013, Pages 485-492
 
Berker Y, Goedicke A, Kemerink GJ, Aach T, Schweizer B. Eur. J.
Nucl. Med. Mol. Imaging, Volume 38, Issue 12, December 2011, Pages 2173-2185

Wierts R, de Pont CD, Brans B, Mottaghy FM, Kemerink GJ. 
Methods, Volume 55, Issue 3, November 2011, Pages 196-202

Schweizer B, Schaefer A, Donsch P, Kremp S, Gouverneur E, Farmakis G, Grgic A, Bal M, Kirsch CM, Hellwig D. Eur. J.
Nucl. Med. Mol. Imaging, Volume 36, Issue 2 Supplement, September 2009, Page 428
 
Grassi E, Fioroni F, Ferri V, Mezzenga E, Sarti M.A., Paulus T, Lanconelli N, Filice A, Versari A, Iori M.
Physica Medica: European Journal of Medical Physics, Volume 31, Issue 1, October 2014, Pages 72-79
 
Wissmeyer A, Delattre BMA, Zaidi H, Terraz S, Ratib O.
Clin Nucl Med., Volume 40, Issue 4, April 2015, Pages 355-357
 

 

 

Caution: Imalytics and its modules are for research purposes only. Not for patient diagnosis or patient treatment planning.