Voxulus
Pharmacokinetic Modeling
• efficient computation of parametric maps based on fully analytical mathematical solution Available compartment models include: • Generic 1 and 2-tissue compartments
VOXULUS is a pharmacokinetic modeling research software, which allows you to obtain quantitative parameters from dynamic imaging data. The available models support your research in many areas, including studies of metabolic processes, hypoxia, cell proliferation, perfusion and receptor binding studies.
Key features of the VOXULUS Pharmacokinetic research modeling software include:
• voxel-wise and regional parameter estimation
• statistical analysis of modeling results, correlation plots and histograms.
• full control over model parameters setup
• flexible combination of models for input and target function
• possibility to define your own analysis protocols
• Blood flow models with 1 and 2-tissue compartments
• FMISO/FAZA 2 and 3-tissue compartments
• Lammertsma and simplified Lammertsma reference tissue models
• Mono-exponential ADC model
Publications
Nucl. Med, Volume 53, Issue 10, October 2012, Pages 1608-1615
Nucl. Med, Volume 51, Issue 1, January 2010, Pages 37-45
Wang W, Georgi JC, Nehmeh SA, Narayanan M, Paulus T, Bal M, O'Donoghue J, Zanzonico PB, Schmidtlein CR, Lee NY, Humm JL.
Phys. Med. Biol, Volume 21, Issue 54, 21 May 2009, Pages 3083-3099
Thiele F, Ehmer J, Piroth MD, Eble MJ, Coenen HH, Kaiser HJ, Schaefer WM, Buell U, Boy C.
Phys. Med. Biol, Volume 54, Issue 18, 2009, Pagea 5525-5539
Publications continued
Nucl. Med. Commun, Volume 29, Issue 2, February 2008
Buchert R, Thiele F, Thomasius R, Wilke F, Petersen K, Brenner W, Mester J, Spies L, Clausen M. J. Psychopharmacol, Volume 21, August 2007, Pages 628-634
Caution: Imalytics and its modules are for research purposes only. Not for patient diagnosis or patient treatment planning.
